Urinary Melatonin Levels, Sleep Disruption, and Risk of Prostate Cancer in Elderly Men
نویسندگان
چکیده
منابع مشابه
Re: Urinary Melatonin Levels, Sleep Disruption, and Risk of Prostate Cancer in Elderly Men.
UNLABELLED Melatonin has anticarcinogenic properties in experimental models. We undertook a case-cohort study of 928 Icelandic men without prostate cancer (PCa) nested within the Age, Gene/Environment Susceptibility (AGES)-Reykjavik cohort to investigate the prospective association between first morning-void urinary 6-sulfatoxymelatonin (aMT6s) levels and the subsequent risk for PCa, under the ...
متن کاملUrinary Melatonin Levels, Sleep Disruption, and Risk of Prostate Cancer in Elderly Men
Centre of Public Health Sciences, University of Iceland, Reykjavik, Iceland; b Faculty of Medicine, University of Iceland, Reykjavik, Iceland; c The Icelandic Cancer Society, Reykjavik, Iceland; Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA; Channing Division of Network Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA; Department of ...
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BACKGROUND Although positive associations have consistently been reported between sleep disruption and breast cancer, less is known about its potential role in prostate cancer. METHODS Within the prospective AGES-Reykjavik cohort study, we followed 2,102 men recruited in 2002-2006 until the end of 2009. Participants answered questions on sleep disruption. Information on the occurrence of pros...
متن کاملUrinary melatonin levels and breast cancer risk.
Exposure to light at night suppresses melatonin production, and night-shift work (a surrogate for such exposure) has been associated with an increased risk of breast cancer. However, the association between circulating melatonin levels and breast cancer risk is unclear. In a prospective case-control study nested within the Nurses' Health Study II cohort, we measured the concentration of the maj...
متن کاملUrinary Melatonin Levels and Skin Malignancy
Melatonin inhibits tumor genesis in a variety of in vivo and in vitro experimental models of neoplasia. In industrialized societies, light at night, by suppressing melatonin production, poses a new risk for the development of a variety of cancers such as breast cancer. This effect on skin has been previously studied only in animals and not in humans. Our goal was to examine the relationship bet...
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ژورنال
عنوان ژورنال: European Urology
سال: 2015
ISSN: 0302-2838
DOI: 10.1016/j.eururo.2014.07.008